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Cayman Opicapone
List Price $113.00 Your Price $113.00
Cayman Opicapone - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-34253-10
MFG.PART: 34253-10
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
Opicapone is a peripherally selective inhibitor of catechol-O-methyltransferase (COMT).1 It inhibits COMT activity in rat liver, but not brain, homogenates (ED50 = 1.05 mg/kg). Opicapone (3 mg/kg) increases plasma levels of L-DOPA (Item No. 13248) and reduces plasma levels of 3-O-methyl-DOPA (3-OMD) when administered in combination with benserazide (Item No. 20298) and L-DOPA.2 Formulations containing opicapone have been used as adjuvants in the treatment of “off” episodes associated with Parkinson’s disease.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[3-(2,5-di chloro-4,6- dimethyl-1- oxido-3- pyridinyl)-1, 2,4-oxadiazol- 5-yl]-3-nitro- 1,2-benzene diol
CAS Number
923287-50-7
Synonyms
- BIA 9-1067
Molecular Formula
C15H10Cl2N4O6
Formula Weight
413.2
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- :
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
SMILES
OC1=CC(C2=NC(C(C(C)=C3Cl)=C([N](=O)=C3C)Cl)=NO2)=CC([N+]([O-])=O)=C1O
InChi Code
InChI=1S/C15H10Cl2N4O6/c1-5-10(13(17)20(24)6(2)11(5)16)14-18-15(27-19-14)7-3-8(21(25)26)12(23)9(22)4-7/h3-4,22-23H,1-2H3
InChi Key
ASOADIZOVZTJSR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34253-10 |
|---|---|
| Supplier Part Number | 34253-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 923287-50-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |

