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Cayman Curcumin analog C1
List Price
$183.00
Your Price
$183.00
Cayman Curcumin analog C1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-34255-10
MFG.PART:
34255-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Curcumin analog C1 is a synthetic curcuminoid.1,2 It inhibits the proliferation of HCT116 colon cancer cells (GI50 = 4 µM).1 Curcumin analog C1 (1 µM) activates transcription factor EB (TFEB), inducing nuclear translocation in Neuro2a mouse neuroblastoma cells.2 It increases LC3-II levels and promotes autophagic flux in Neuro2a cells when used at a concentration of 1 µM. Curcumin analog C1 (10 and 25 mg/kg, p.o.) activates TFEB and increases autophagy and lysosome biogenesis in rat brain.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(1E,4E)-1,5-
CAS Number
39777-61-2
Synonyms
- GO-Y019
- TFEB Activator 1
Molecular Formula
C19H18O3
Formula Weight
294.3
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 1 mg/mL
λmax
366 nm
SMILES
COC1=C(/C=C/C(/C=C/C2=C(OC)C=CC=C2)=O)C=CC=C1
InChi Code
InChI=1S/C19H18O3/c1-21-18-9-5-3-7-15(18)11-13-17(20)14-12-16-8-4-6-10-19(16)22-2/h3-14H,1-2H3/b13-11+,14-12+
InChi Key
RCZMPCUUTSDNAJ-PHEQNACWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34255-10 |
|---|---|
| Supplier Part Number | 34255-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 39777-61-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |