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Cayman LC3-mHTT-IN-AN1
List Price $98.00 Your Price $98.00
Cayman LC3-mHTT-IN-AN1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-34306-5
MFG.PART: 34306-5
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
LC3-mHTT-IN-AN1 is a linker molecule that interacts with the autophagosome protein microtubule-associated protein 1 light chain 3β (LC3B) and mutant huntingtin (Hdh).1 It decreases HdhQ7/Q140, but not wild-type huntingtin, levels in primary mouse cortical neurons when used at a concentration of 300 nM. LC3-mHTT-IN-AN1 increases survival of Drosophila expressing human HdhQ128.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-bromo-3-[(3-
CAS Number
486443-73-6
Molecular Formula
C15H9Br2NO3
Formula Weight
411.0
Purity
≥95% (mixture of cis and trans isomers)
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:3): 0.25 mg/mL
λmax
260, 372 nm
SMILES
O=C1NC2=CC=C(C=C2C1=CC3=CC(Br)=C(C(O)=C3)O)Br
InChi Code
InChI=1S/C15H9Br2NO3/c16-8-1-2-12-9(6-8)10(15(21)18-12)3-7-4-11(17)14(20)13(19)5-7/h1-6,19-20H,(H,18,21)
InChi Key
GPKLWRHHVIBYEO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34306-5 |
|---|---|
| Supplier Part Number | 34306-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 486443-73-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |