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Cayman DLin-MC3-DMA
List Price
$141.00
Your Price
$141.00
Cayman DLin-MC3-DMA - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-34364-25
MFG.PART:
34364-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
DLin-MC3-DMA is an ionizable cationic amino lipid (apparent pKa = 6.44) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs).1 Administration of Factor VII siRNA in DLin-MC3-DMA-containing LNPs reduces plasma Factor VII protein levels in mice. Formulations containing DLin-MC3-DMA have been used in the development of LNPs for siRNA delivery in patients with hereditary transthyretin-mediated amyloidosis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(dimethyl amino)- butanoic acid, (10Z,13Z)-1- (9Z,12Z)-9,12- octadecadien- 1-yl-10,13- nonadecadien- 1-yl ester
CAS Number
1224606-06-7
Synonyms
- MC3
Molecular Formula
C43H79NO2
Formula Weight
642.1
Purity
≥95%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- DMSO: Soluble
- Ethanol: 100 mg/mL
λmax
204 nm
SMILES
CCCCC\C=C/C\C=C/CCCCCCCCC(CCCCCCCC\C=C/C\C=C/CCCCC)OC(=O)CCCN(C)C
InChi Code
InChI=1S/C43H79NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-38-42(46-43(45)40-37-41-44(3)4)39-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h13-16,19-22,42H,5-12,17-18,23-41H2,1-4H3/b15-13-,16-14-,21-19-,22-20-
InChi Key
NRLNQCOGCKAESA-KWXKLSQISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-34364-25 |
|---|---|
| Supplier Part Number | 34364-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 1224606-06-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |