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Cayman Oxaliplatin-d10
List Price $1,056.00 Your Price $1,056.00
Cayman Oxaliplatin-d10 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-34408-1
MFG.PART: 34408-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin (Item No. 13106) by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent.1 It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2.7 µM, respectively).2 It reduces tumor growth in an HCCLM3 mouse xenograft model when administered at doses of 5 or 10 mg/kg once per week.3 Formulations containing oxaliplatin have been used in the treatment of advanced colorectal cancer and as adjuvants in stage III colon cancer.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(SP-4-2)-[(1R,
CAS Number
1132819-16-9
Synonyms
- Lipoxal-d10
Molecular Formula
C8H4D10N2O4Pt
Formula Weight
407.4
Purity
≥99% deuterated forms (d1-d10)
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: slightly soluble
- Water: slightly, sonicated
SMILES
O=C1[O-][Pt+2]2([O-]C1=O)[NH2][C@@](C([2H])([2H])C([2H])([2H])C([2H])([2H])C3([2H])[2H])([2H])[C@]3([2H])[NH2]2
InChi Code
InChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2/t5-,6-;;/m1../s1/i1D2,2D2,3D2,4D2,5D,6D;;
InChi Key
ZROHGHOFXNOHSO-YYKMXZQESA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34408-1 |
|---|---|
| Supplier Part Number | 34408-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 1132819-16-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |