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Cayman Ro 04-6790 (hydrochloride hydrate)
List Price $713.00 Your Price $713.00
Cayman Ro 04-6790 (hydrochloride hydrate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-34476-25
MFG.PART: 34476-25
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
Ro 04-6790 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT6 (Ki = 44.7 nM).1 It is selective for 5-HT6 receptors over a panel of 23 additional receptors at 10 µM. Ro 04-6790 inhibits 5-HT-induced cAMP production in HeLa cells expressing human 5-HT6 (PA2 = 6.75). In vivo, Ro 04-6790 (10 and 30 mg/kg) induces stretching and yawning behavior in rats. It reverses scopolamine-induced decreases in novel object discrimination in rats.2 Ro 04-6790 (3, 10, and 30 mg/kg) also attenuates cue-induced cocaine-seeking behavior in rats.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-amino-N- [2,6-bis (methylamino)- 4-pyrimidinyl]- benzene sulfonamide, dihydro chloride hydrate
Molecular Formula
C12H16N6O2S • 2HCl [XH2O]
Formula Weight
381.3
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: 15 mg/mL
- Water: 5 mg/mL
SMILES
O=S(NC1=NC(NC)=NC(NC)=C1)(C2=CC=C(C=C2)N)=O.Cl.Cl.O
InChi Code
InChI=1S/C12H16N6O2S.2ClH.H2O/c1-14-10-7-11(17-12(15-2)16-10)18-21(19,20)9-5-3-8(13)4-6-9;;;/h3-7H,13H2,1-2H3,(H3,14,15,16,17,18);2*1H;1H2
InChi Key
NAXNKMHJJJLURY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34476-25 |
|---|---|
| Supplier Part Number | 34476-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |

