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Cayman (±)12-HETE
List Price $165.00 Your Price $165.00
Cayman (±)12-HETE - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-34550-50
MFG.PART: 34550-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
(±)12-HETE is a racemic mixture of the arachidonic acid metabolites 12(R)-HETE (Item No. 34560) and 12(S)-HETE (Item No. 34570). It is formed via non-enzymatic oxidation of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607).1,2 12(S)- and 12(R)-HETE are formed by 12S- and 12R-lipoxygenase-mediated oxidation of arachidonic acid, respectively.3,4,5 12(R)-HETE can also be formed by oxidation of arachidonic acid mediated by cytochrome P450 (CYP450) enzymes.1 (±)12-HETE (1 µM) induces aggregation of isolated human neutrophils.6 Production of (±)12-HETE by platelets isolated from spontaneously hypertensive rats is increased compared with platelets isolated from normotensive rats.7
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(±)12-
CAS Number
71030-37-0
Synonyms
- (±)12-Hydroxyeicosatetraenoic Acid
Molecular Formula
C20H32O3
Formula Weight
320.5
Purity
≥95%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- 0.1 M Na2CO3: 2 mg/mL
- DMF: Miscible
- DMSO: Miscible
- Ethanol: Miscible
- PBS (pH 7.2): 0.8 mg/mL
λmax
237 nm
SMILES
CCCCC/C=C\CC(O)/C=C/C=C\C/C=C\CCCC(O)=O
InChi Code
InChI=1S/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+
InChi Key
ZNHVWPKMFKADKW-VXBMJZGYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-34550-50 |
|---|---|
| Supplier Part Number | 34550-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 71030-37-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |