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Cayman Deltorphin II (trifluoroacetate salt)
List Price $81.00 Your Price $81.00
Cayman Deltorphin II (trifluoroacetate salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-34691-1
MFG.PART: 34691-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2 It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 µM, respectively) and induces [35S]GTPγS binding in mouse brain membrane preparations (EC50 = 0.034 µM). Deltorphin II (0.12 mg/kg) decreases the infarction zone:risk zone ratio in a rat model of myocardial ischemia-reperfusion injury induced by coronary occlusion, an effect that can be reversed by the δ2-opioid receptor antagonist naltriben but not the δ1-opioid receptor antagonist BNTX.3 Intrathecal administration of deltorphin II (15 µg/animal) increases latency to withdraw in the paw pressure and tail-flick tests in rats.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
L-tyrosyl-D-
Synonyms
- DADELT II
- [D-Ala2]Deltorphin II
- [D-Ala2, Glu4]Deltorphin II
- Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2
Molecular Formula
C38H54N8O10 • XCF3COOH
Formula Weight
782.9
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 15 mg/mL
- DMF:PBS (pH 7.2) (1:5): 0.16 mg/mL
- DMSO: 1 mg/mL
- Ethanol: slightly soluble
SMILES
NC(CNC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@@H](C)NC([C@@H](N)CC1=CC=C(C=C1)O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C38H54N8O10.C2HF3O2/c1-20(2)31(37(55)41-19-29(40)48)46-38(56)32(21(3)4)45-35(53)27(15-16-30(49)50)43-36(54)28(18-23-9-7-6-8-10-23)44-33(51)22(5)42-34(52)26(39)17-24-11-13-25(47)14-12-24;3-2(4,5)1(6)7/h6-14,20-22,26-28,31-32,47H,15-19,39H2,1-5H3,(H2,40,48)(H,41,55)(H,42,52)(H,43,54)(H,44,51)(H,45,53)(H,46,56)(H,49,50);(H,6,7)/t22-,26+,27+,28+,31+,32+;/m1./s1
InChi Key
HCWNUZKKWMPYQE-CEULVJOSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34691-1 |
|---|---|
| Supplier Part Number | 34691-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |