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Cayman Ubiquitin Remnant (K-ε-GG) Immunoaffinity Sorbent
List Price
$407.00
Your Price
$407.00
Cayman Ubiquitin Remnant (K-ε-GG) Immunoaffinity Sorbent - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-34699-400
MFG.PART:
34699-400
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Dofetilide is a class III antiarrhythmic agent that prolongs cardiac action potential duration by selectively inhibiting the rapidly activating inward rectifying component of net delayed rectifier K+ current (IC50 = 31.5 nM in guinea pig cardiomyocytes). However, at 1 μM, dofetilide has pro-arrhythmic activity, inducing early afterdepolarizations (prolonged repolarization) in cell models and Torsade de Pointes in a rabbit screen for proarrhythmic properties when administered at a dose of 10 mg/kg. Formulations containing dofetilide have been used in the treatment of highly symptomatic atrial fibrillation and the conversion of flutter to normal sinus rhythm.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-
CAS Number
115256-11-6
Synonyms
- Tikosyn
- UK 68789
Molecular Formula
C19H27N3O5S2
Formula Weight
441.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS (pH 7.2) (1:20): 0.4 mg/ml
λmax
232 nm
SMILES
CS(NC1=CC=C(OCCN(C)CCC2=CC=C(NS(C)(=O)=O)C=C2)C=C1)(=O)=O
InChi Code
InChI=1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3
InChi Key
IXTMWRCNAAVVAI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34699-400 |
|---|---|
| Featured | No |
| Supplier Part Number | 34699-400 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | 4 |
| Refrigerated-Frozen | Refrigerated |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |