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Cayman Cyclo(RGDyK) (trifluoroacetate salt)
List Price
$54.00
Your Price
$54.00
Cayman Cyclo(RGDyK) (trifluoroacetate salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-35173-1
MFG.PART:
35173-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Cyclo(RGDyK) is a cyclic peptide ligand of αVβ3 integrin (IC50 = 37.5 nM) that contains the αVβ3 integrin-binding sequence arginine-glycine-aspartate (RGD).1 It has been conjugated to radiolabels or fluorescent probes for the visualization of αVβ3-mediated neoangiogenesis or optical imaging of αVβ3-expressing tumors in live mice.2,1 Cyclo(RGDyK) has also been conjugated to the DNA topoisomerase I inhibitor SN38 (Item No. 15632) and an SN38-releasing trigger moiety to form a prodrug that targets cells overexpressing αVβ3 integrin and induces cytotoxicity in KB human cervical carcinoma cells.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
cyclo(L-arginyl
Synonyms
- c(RGDyK)
- cyclic-L-Arg-L-Gly-L-Asp-D-Tyr-L-Lys
Molecular Formula
C27H41N9O8 • XCF3COOH
Formula Weight
619.7
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- Ethanol: soluble
- Water: soluble
λmax
225 nm
SMILES
O=C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCCCN)[C@H]1CC2=CC=C(C=C2)O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C27H41N9O8.C2HF3O2/c28-10-2-1-4-18-24(42)34-17(5-3-11-31-27(29)30)23(41)32-14-21(38)33-20(13-22(39)40)26(44)36-19(25(43)35-18)12-15-6-8-16(37)9-7-15;3-2(4,5)1(6)7/h6-9,17-20,37H,1-5,10-14,28H2,(H,32,41)(H,33,38)(H,34,42)(H,35,43)(H,36,44)(H,39,40)(H4,29,30,31);(H,6,7)/t17-,18-,19+,20-;/m0./s1
InChi Key
KTQFOJMRRQLTAN-HXSCNMCGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-35173-1 |
|---|---|
| Supplier Part Number | 35173-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |