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Cayman 5(S),12(S)-DiHETE
List Price $636.00 Your Price $636.00
Cayman 5(S),12(S)-DiHETE - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-35260-100
MFG.PART: 35260-100
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid (AA; Item No. ). It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5(S),12(S)-DiHETE can be produced by successive oxygenation of AA by 5-lipoxygenase (5-LO) in platelets and 12-LO in leukocytes. It can also be synthesized from 12(S)-HETE by 5-LO, in the presence of 5-LO activating protein (FLAP), activated with calcium ionophore. 5(S),12(S)-DiHETE is an epimer of leukotriene B4 (Item No. ) that is weakly chemotactic for PMNL.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5S,12S-
CAS Number
79056-01-2
Molecular Formula
C20H32O4
Formula Weight
336.5
Purity
≥98%
Formulation
A solution in ethanol
Solubility
- DMF: 50 mg/mL
- DMSO: 50 mg/mL
- Ethanol: 50 mg/mL
- PBS (pH 7.2): 1 mg/mL
λmax
268 nm
SMILES
CCCCC/C=C\C[C@H](O)/C=C/C=C\C=C\[C@@H](O)CCCC(O)=O
InChi Code
InChI=1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7-,9-6-,14-10+,15-11+/t18-,19+/m0/s1
InChi Key
VNYSSYRCGWBHLG-RYYHSVJXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-35260-100 |
|---|---|
| Supplier Part Number | 35260-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 79056-01-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |