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Cayman 5(S),12(S)-DiHETE
List Price $337.00 Your Price $337.00
Cayman 5(S),12(S)-DiHETE - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-35260-50
MFG.PART: 35260-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid (AA; Item No. 10006607). It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA.1 5(S),12(S)-DiHETE can be produced by successive oxygenation of AA by 5-lipoxygenase (5-LO) in platelets and 12-LO in leukocytes.2 It can also be synthesized from 12(S)-HETE by 5-LO, in the presence of 5-LO activating protein (FLAP), activated with calcium ionophore.3 5(S),12(S)-DiHETE is an epimer of leukotriene B4 (Item No. 20110) that is weakly chemotactic for PMNL.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5S,12S-
CAS Number
79056-01-2
Molecular Formula
C20H32O4
Formula Weight
336.5
Purity
≥98%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- DMF: 50 mg/mL
- DMSO: 50 mg/mL
- Ethanol: 50 mg/mL
- PBS (pH 7.2): 1 mg/mL
λmax
268 nm
SMILES
CCCCC/C=C\C[C@H](O)/C=C/C=C\C=C\[C@@H](O)CCCC(O)=O
InChi Code
InChI=1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7-,9-6-,14-10+,15-11+/t18-,19+/m0/s1
InChi Key
VNYSSYRCGWBHLG-RYYHSVJXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-35260-50 |
|---|---|
| Supplier Part Number | 35260-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 79056-01-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |