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Cayman Nkx3.1 (N-Term) Rabbit Monoclonal Antibody, Size100 Μl
List Price
$380.00
Your Price
$380.00
Cayman Nkx3.1 (N-Term) Rabbit Monoclonal Antibody, Size - 100 Μl - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-35320-100
MFG.PART:
35320-100
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Dexamethasone phosphate is a glucocorticoid. It reduces LPS-induced production of RANTES, TGF-β1, and nitric oxide (NO) in BV-2 microglia when used at concentrations ranging from 1 to 4 µM. Dexamethasone phosphate reverses LPS-induced decreases in IL-10 levels in, and inhibits LPS-induced migration of, BV-2 microglia when used at a concentration of 4 µM. In vivo, dexamethasone phosphate decreases motor activity and reduces adrenal weight and plasma corticosterone levels in rats when administered in the drinking water at a concentration of 5 µg/ml. Dexamethasone phosphate (1.6 mg/kg per day) reduces joint swelling in a rat model of collagen-induced arthritis when administered for a minimum of seven days. It also reduces pruritis and the clinical lesion score in cats with hypersensitivity dermatitis. Formulations containing dexamethasone phosphate have been used in the treatment of various inflammatory diseases, arthritis, and endocrine disorders.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(11β,16α)-9-
CAS Number
2392-39-4
Synonyms
- Dexamethasone 21-phosphate
- Dexamethasone Sodium Phosphate
Molecular Formula
C22H28FO8P • 2Na
Formula Weight
516.4
Purity
≥95%
Formulation
A crystalline solid
Solubility
- PBS (pH 7.2): 10 mg/ml
- Water: 30 mg/ml
λmax
239 nm
SMILES
O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@@H](C)[C@]4(O)C(COP([O-])([O-])=O)=O)=C1.[Na+].[Na+]
InChi Code
InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1
InChi Key
PLCQGRYPOISRTQ-FCJDYXGNSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-35320-100 |
|---|---|
| Featured | No |
| Supplier Part Number | 35320-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |