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Cayman Cu-ATSP
List Price
$36.00
Your Price
$36.00
Cayman Cu-ATSP - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-35322-1
MFG.PART:
35322-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Cu-ATSP is a copper-containing bis(thiosemicarbazone) complex with ferroptosis inhibitory activity.1 It traps peroxyl radicals in a cell-free assay when used at a concentration of 6 µM. Cu-ATSP inhibits ferroptosis induced by (1S,3R)-RSL3 (Item No. 19288) in Pfa1 mouse embryonic fibroblasts (MEFs) and HT22 mouse hippocampal cells (EC50s = 8.5 and 16 nM, respectively). It increases intracellular copper levels but, unlike the bis(thiosemicarbazone) complexes Cu-CQ2 and CuNC2, does not reduce amyloid-β (1-40) (Aβ40) levels in CHO Cells overexpressing amyloid precursor protein (APP).2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(SP-4-2)-[[2, 2′-(1,2-dimethyl-1,2-ethanediylidene)bis[N-phenylhydrazinecarbothioamidato-κN2,κS]](2-)]-copper
CAS Number
68341-12-8
Synonyms
- copper-ATSP
- CuII(atsp)
Molecular Formula
C18H18CuN6S2
Formula Weight
446.1
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 1 mg/mL
λmax
247, 315, 395, 494 nm
SMILES
CC1=[N-]2N=C(NC3=CC=CC=C3)S[Cu+2]42SC(NC5=CC=CC=C5)=N[N-]4=C1C
InChi Code
InChI=1S/C18H20N6S2.Cu/c1-13(21-23-17(25)19-15-9-5-3-6-10-15)14(2)22-24-18(26)20-16-11-7-4-8-12-16;/h3-12H,1-2H3,(H2,19,23,25)(H2,20,24,26);/q;+2/p-2/b21-13+,22-14+;
InChi Key
YYPBOUNODSJBJR-JKBLJYNNSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-35322-1 |
|---|---|
| Supplier Part Number | 35322-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 68341-12-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |