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Cayman DPPE (fumarate)
List Price $141.00 Your Price $141.00
Cayman DPPE (fumarate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-35360-10
MFG.PART: 35360-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
DPPE is a ligand for the antiestrogen-binding site (AEBS; Ki = 55.6 nM in rat liver microsomes) and derivative of tamoxifen (Item No. 11629).1 It is selective for the AEBS over the estrogen receptor when used at a concentration of 10 µM. DPPE is cytotoxic to S10 and MCF-7 cells (IC50s = 7.5 and 12 µM) and inhibits antigen-induced histamine release in isolated rat mast cells (IC50 = 65-85 µM).2,3 It decreases uterine size in immature oophorectomized rats in a dose-dependent manner.4 DPPE (4 mg/kg) protects bone marrow progenitor cells from cytotoxicity induced by doxorubicin (Item No. 15007) in mice.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N,N-diethyl-
CAS Number
1185241-83-1
Synonyms
- BMS-217380-01
- Tesmilifene
Molecular Formula
C19H25NO • C4H4O4
Formula Weight
399.5
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: soluble
SMILES
O=C(C=CC(O)=O)O.CCN(CC)CCOC1=CC=C(CC2=CC=CC=C2)C=C1
InChi Code
InChI=1S/C19H25NO.C4H4O4/c1-3-20(4-2)14-15-21-19-12-10-18(11-13-19)16-17-8-6-5-7-9-17;5-3(6)1-2-4(7)8/h5-13H,3-4,14-16H2,1-2H3;1-2H,(H,5,6)(H,7,8)
InChi Key
ZOOMDYHTGZSGDD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-35360-10 |
|---|---|
| Supplier Part Number | 35360-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1185241-83-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |