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Cayman α-Arbutin
List Price $41.00 Your Price $41.00
Cayman α-Arbutin - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-35386-5
MFG.PART: 35386-5
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
α-Arbutin is a glycosylated hydroquinone that has been found in Ericaceae and has diverse biological activities.1,2,3,4,5 It inhibits tyrosinase in a cell-free assay (IC50 = 0.48 mm for the mouse enzyme) and the production of melanin in HMV-II melanoma cells when used at a concentration of 0.5 mm.1,2 α-Arbutin (100 µM) prevents increases in reactive oxygen species (ROS) induced by rotenone (Item No. 13995) in SH-SY5Y neuroblastoma cells.3 It decreases locomotor deficits in a parkin-null transgenic Drosophila model of Parkinson’s disease. α-Arbutin (30 mm) reduces postprandial plasma glucose levels in mice.4 It has also been used in the synthesis of α-glucosidase inhibitors.5 Formulations containing α-arbutin have been used in cosmetic products as skin lightening agents.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-hydroxyphenyl α-D-
CAS Number
84380-01-8
Synonyms
- Hydroquinone α-Glucoside
- Hydroquinone O-α-D-Glucopyranoside
- 4-Hydroxyphenyl α-Glucoside
- 4-Hydroxyphenyl α-Glucopyranoside
Molecular Formula
C12H16O7
Formula Weight
272.3
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 15 mg/mL
- Ethanol: 1 mg/mL
- PBS (pH 7.2): 5 mg/mL
λmax
224 nm
SMILES
O[C@@H]1[C@@H](O)[C@@H](OC2=CC=C(O)C=C2)O[C@H](CO)[C@H]1O
InChi Code
InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/m1/s1
InChi Key
BJRNKVDFDLYUGJ-ZIQFBCGOSA-N
Origin
Fermentation (species not specified)
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-35386-5 |
|---|---|
| Supplier Part Number | 35386-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 84380-01-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |