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Cayman Dexamethasone Palmitate
List Price
$239.00
Your Price
$239.00
Cayman Dexamethasone Palmitate - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-35451-25
MFG.PART:
35451-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Dexamethasone palmitate is a prodrug form of the synthetic glucocorticoid dexamethasone (Item No. 11015).1 It binds to the glucocorticoid receptor.2 Dexamethasone palmitate-containing lipid nanoparticles reduce LPS-induced increases in cytokine levels in RAW 264.7 macrophages when used at a concentration of 100 µg/mL.3 Dexamethasone palmitate reduces paw inflammation and edema in a mouse model of collagen-induced rheumatoid arthritis when administered at a dose of 1 mg/kg. Intravitreal injection of a dexamethasone palmitate (1,280 µg/animal) emulsion inhibits vascular hyperpermeability induced by VEGF for up to nine months in rabbits.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
9-fluoro-11β,
CAS Number
14899-36-6
Synonyms
- Dexamethasone 21-palmitate
- DXP
- Limethason
Molecular Formula
C38H59FO6
Formula Weight
630.9
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/mL
- DMSO: 10 mg/mL
- Ethanol: 16 mg/mL
λmax
239 nm
SMILES
C[C@@]12[C@](C[C@H]([C@]2(O)C(COC(CCCCCCCCCCCCCCC)=O)=O)C)([H])[C@@]3([H])[C@@]([C@@]4(C(CC3)=CC(C=C4)=O)C)([C@H](C1)O)F
InChi Code
InChI=1S/C38H59FO6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-34(43)45-26-33(42)38(44)27(2)23-31-30-20-19-28-24-29(40)21-22-35(28,3)37(30,39)32(41)25-36(31,38)4/h21-22,24,27,30-32,41,44H,5-20,23,25-26H2,1-4H3/t27-,30+,31+,32+,35+,36+,37+,38+/m1/s1
InChi Key
WDPYZTKOEFDTCU-WDJQFAPHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-35451-25 |
|---|---|
| Supplier Part Number | 35451-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 14899-36-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |