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Cayman ICI 63197
List Price $178.00 Your Price $178.00
Cayman ICI 63197 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-35538-100
MFG.PART: 35538-100
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
ICI 63197 is an inhibitor of phosphodiesterase 3 (PDE3) and PDE4 (Kis = 9 and 10 µM, respectively).1 It is selective for PDE3 and PDE4 over PDE1 and PDE2 (Kis = 487 and >1,000 µM, respectively). ICI 63197 inhibits acetylcholine-induced bronchospasm in isolated guinea pig lungs and histamine-induced bronchospasm in conscious guinea pigs.2 It decreases motor activity and rectal temperature and induces forepaw shaking, head twitches, and grooming in rats in a dose-dependent manner.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-amino-6- methyl-4- propyl-[1,2,4] triazolo[1,5-a] pyrimidin- 5(4H)-one
CAS Number
27277-00-5
Molecular Formula
C9H13N5O
Formula Weight
207.2
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 10 mg/mL
- Ethanol: Slightly soluble
- PBS (pH 7.2): 0.2 mg/mL
λmax
224, 307 nm
SMILES
O=C1C(C)=CN2N=C(N)N=C2N1CCC
InChi Code
InChI=1S/C9H13N5O/c1-3-4-13-7(15)6(2)5-14-9(13)11-8(10)12-14/h5H,3-4H2,1-2H3,(H2,10,12)
InChi Key
UQDVRVNMIJAGRK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-35538-100 |
|---|---|
| Supplier Part Number | 35538-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 27277-00-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |

