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Cayman AT-001
List Price $1,005.00 Your Price $1,005.00
Cayman AT-001 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-36105-25
MFG.PART: 36105-25
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
AT-001 is an inhibitor of aldose reductase (IC50 = 28.9 pM).1 It reduces infarct area in streptozotocin-induced diabetic mice expressing human aldose reductase in a model of cardiomyopathy induced by ischemia-reperfusion injury when administered at a dose of 40 mg/kg.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7,8-dihydro- 8-oxo-7-[[5- (trifluoro methyl)-2- benzo thiazolyl] methyl]- pyrazino[2,3- d]pyridazine- 5-acetic acid
CAS Number
1355612-71-3
Synonyms
- Caficrestat
Molecular Formula
C17H10F3N5O3S
Formula Weight
421.4
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: soluble
λmax
221, 257 nm
SMILES
O=C(CC1=NN(CC2=NC3=C(S2)C=CC(C(F)(F)F)=C3)C(C4=NC=CN=C41)=O)O
InChi Code
InChI=1S/C17H10F3N5O3S/C18-17(19,20)8-1-2-11-9(5-8)23-12(29-11)7-25-16(28)15-14(21-3-4-22-15)10(24-25)6-13(26)27/h1-5H,6-7H2,(H,26,27)
InChi Key
YRGPAXAVTDMKDK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-36105-25 |
|---|---|
| Supplier Part Number | 36105-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1355612-71-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |

