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Cayman Nipecotic Acid
List Price $74.00 Your Price $74.00
Cayman Nipecotic Acid - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-36126-250
MFG.PART: 36126-250
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Nipecotic acid is an inhibitor of GABA transporters (GAT; IC50s = 2.6, 310, 29, and 16 µM for mouse GAT-1, GAT-2, GAT-3, and GAT-4, respectively).1 It does not bind GABAA or GABAB receptors (IC50s = >100 µM for both) but does bind the adenosine A3 receptor (IC50 = 0.01 µM).2,3 Nipecotic acid inhibits GABA uptake in isolated rabbit choroid plexus (IC50 = 244 µM).4 It inhibits lactate dehydrogenase (LDH) release (EC50 = ~5 µM) and aggregation of a mutant form of huntingtin, htt-N63-148Q, in PC12 cells.5 Intraventricular administration of nipecotic acid (300 µg/animal) decreases tail flick reaction time in a rat model of morphine-induced analgesia.6
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-piperidine
CAS Number
498-95-3
Synonyms
- (±)-Nipecotic Acid
- (R,S)-Nipecotic Acid
- 3-Piperidine Carboxylic Acid
- DL-Piperidine 3-Carboxylic Acid
Molecular Formula
C6H11NO2
Formula Weight
129.2
Purity
≥95%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: Slightly soluble
- DMSO: Slightly soluble
- Ethanol: Slightly soluble
- PBS (pH 7.2): 10 mg/mL
SMILES
O=C(C1CCCNC1)O
InChi Code
InChI=1S/C6H11NO2/C8-6(9)5-2-1-3-7-4-5/h5,7H,1-4H2,(H,8,9)
InChi Key
XJLSEXAGTJCILF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-36126-250 |
|---|---|
| Supplier Part Number | 36126-250 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 498-95-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |