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Cayman BRM/BRG1 ATP Inhibitor 1
List Price
$610.00
Your Price
$610.00
Cayman BRM/BRG1 ATP Inhibitor 1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-36138-10
MFG.PART:
36138-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
BRM/BRG1 ATP inhibitor 1 is an allosteric dual inhibitor of brahma homologue (BRM), also known as SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 2 (SMARCA2), and brahma-related gene 1 (BRG1), also known as SMARCA4, ATPase activities (IC50s = <0.005 µM for both).1 It reduces the expression of keratin 80 (KRT80) in H1299 and RERF-LC-A1 cells. BRM (20mg/kg) reduces tumor growth in a RERF-LC-A1 lung cancer mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[3-(difluoro
CAS Number
2270879-17-7
Synonyms
- Brahma Homologue/Brahma-related Gene 1 Adenosine 5-triphosphate Inhibitor 1
Molecular Formula
C11H9F3N4O2S
Formula Weight
318.3
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: Soluble
λmax
276 nm
SMILES
O=C(NC1=CC(F)=NC=C1CO)NC2=CC(C(F)F)=NS2
InChi Code
InChI=1S/C11H9F3N4O2S/c12-8-1-6(5(4-19)3-15-8)16-11(20)17-9-2-7(10(13)14)18-21-9/h1-3,10,19H,4H2,(H2,15,16,17,20)
InChi Key
CKYCAIAVJIFWPE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-36138-10 |
|---|---|
| Supplier Part Number | 36138-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2270879-17-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |