Cayman Wrw4 (Trifluoroacetate Salt)

CV-6209-d₅ contains five deuterium atoms at the 1, 1, 2, 2, and 2 positions of the ethyl pyridinium moiety. It is intended for use as an internal standard for the quantification of CV-6209 (Item No. ) by GC- or LC-mass spectrometry. CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor, inhibiting aggregation of rabbit and human platelets induced by PAF with IC₅₀ values of 75 and 170 nM, respectively. It has little action on platelet aggregation induced by arachidonic acid, ADP, or collagen. CV-6209 is bioavailable, as it prevents PAF-induced hypotension in rats, while not blocking hypotension triggered by arachidonic acid (Item No. ), histamine, bradykinin (Item No. ), or isoproterenol (Item No. ). CV-6209 is used to study the role of PAF receptor signaling in vitro and in vivo.^,

WARNING This product is not for human or veterinary use.