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Cayman AM92016 (hydrochloride)
List Price $552.00 Your Price $552.00
Cayman AM92016 (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-36803-50
MFG.PART: 36803-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
AM92016 is an inhibitor of delayed-rectifier potassium current (IKr; IC50 = 40 nM in isolated rabbit sinoatrial node cells).1 It is selective for IKr over L-type voltage-gated calcium (Cav) current and hyperpolarization-activated inward current (If) at 1 µM. AM92016 (50 nM) decreases the diastolic depolarization rate and increases cycle length and action potential duration at full repolarization in isolated rabbit sinoatrial node cells. It decreases the QT interval and increases heart rate in anesthetized guinea pigs when administered at a dose of 1 mg/kg.2 AM92016 (1 mg/kg) decreases the time to first arrhythmia and ventricular fibrillation in ouabain-stimulated guinea pigs.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[4-[3-[[2-
CAS Number
133229-11-5
Molecular Formula
C19H24Cl2N2O4S • HCl
Formula Weight
483.8
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 3 mg/mL
- DMSO: 1 mg/mL
- Ethanol: 1 mg/mL
SMILES
O=S(NC1=CC=C(C=C1)OCC(CN(CCC2=CC=C(C(Cl)=C2)Cl)C)O)(C)=O.Cl
InChi Code
InChI=1S/C19H24Cl2N2O4S.ClH/c1-23(10-9-14-3-8-18(20)19(21)11-14)12-16(24)13-27-17-6-4-15(5-7-17)22-28(2,25)26;/h3-8,11,16,22,24H,9-10,12-13H2,1-2H3;1H
InChi Key
TXOARFPCQOBODS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-36803-50 |
|---|---|
| Supplier Part Number | 36803-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 133229-11-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |