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Cayman PTP1B-IN-2
List Price
$159.00
Your Price
$159.00
Cayman PTP1B-IN-2 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-36824-25
MFG.PART:
36824-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
PTP1B-IN-2 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC50 = 50 nM).1 It is selective for PTP1B over T cell protein tyrosine phosphatase (TCPTP), Src homology region 2 domain-containing phosphatase 1 (SHP-1), SHP-2, and leukocyte common antigen-related (LAR) phosphatase (IC50s = 760, 2,450, 2,160, and 12,610 nM, respectively). PTP1B-IN-2 (5-20 µM) enhances insulin-induced glucose uptake in L6 myotubes.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[[[4-[(2-
CAS Number
1919853-46-5
Synonyms
- Protein Tyrosine Phosphatase 1B Inhibitor 2
- PTPN1 Inhibitor 2
- Tyrosine-protein Phosphatase Non-Receptor Type 1 Inhibitor 2
Molecular Formula
C34H36N2O9S2
Formula Weight
680.8
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 10 mg/mL
SMILES
O=C(C1=CC(N(S(=O)(CC2=CC=CC=C2)=O)CC3=CC=C(N(S(=O)(C)=O)CC(OC)=O)C=C3)=CC=C1OCC4=CC=C(C)C=C4)OC
InChi Code
InChI=1S/C34H36N2O9S2/c1-25-10-12-27(13-11-25)23-45-32-19-18-30(20-31(32)34(38)44-3)36(47(41,42)24-28-8-6-5-7-9-28)21-26-14-16-29(17-15-26)35(46(4,39)40)22-33(37)43-2/h5-20H,21-24H2,1-4H3
InChi Key
IPNJQCVHNPGYOX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-36824-25 |
|---|---|
| Supplier Part Number | 36824-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1919853-46-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |