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Cayman Melittin (C-Term Cysteine labeled) (trifluoroacetate salt)
List Price
$146.00
Your Price
$146.00
Cayman Melittin (C-Term Cysteine labeled) (trifluoroacetate salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-37504-1
MFG.PART:
37504-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Melittin (C-term cysteine labeled) is a derivative of the cytotoxic bee venom peptide melittin (Item No. 17494) with a cysteine residue at the C-terminus.1,2 It induces hemolysis of isolated human red blood cells at endosomal and extracellular pHs (EC50s = 5 and 6 µM at pH 5.5 and 7.4, respectively).1 Melittin (C-term cysteine labeled) has been used in the synthesis of membrane-lytic polymers that have been used in the generation of polyplexes for plasmid delivery in vitro and in vivo.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
glycyl-L-ISO leucylglycyl- L-alanyl-L- valyl-L-leucyl- L-lysyl-L- valyl-L-leucyl- L-threonyl-L- threonyl glycyl-L- leucyl-L- prolyl-L- alanyl-L- leucyl-L-ISO leucyl-L-seryl- L-tryptophyl- L-isoleucyl-L- lysyl-L- arginyl-L- lysyl-L- arginyl-L- glutaminyl-L- glutaminyl-L- cysteinamide, trifluoro acetate salt
Synonyms
- Mel-Cys
Molecular Formula
C134H234N40O32S • XCF3COOH
Formula Weight
2949.6
Purity
≥95%
Formulation(Request formulation change)
A solid
Peptide Sequence
GIGAVLKVLTTGLPALISWIKRKRQQC-NH2
Solubility(Learn about Variance in Solubility)
- 30% ACN/H2O: Soluble
λmax
280 nm
SMILES
[H]NCC(N[C@]([C@H](CC)C)([H])C(NCC(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@]([C@@H](C)O)([H])C(N[C@]([C@@H](C)O)([H])C(NCC(N[C@@H](CC(C)C)C(N1CCC[C@H]1C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@]([C@H](CC)C)([H])C(N[C@@H](CO)C(N[C@H](C(N[C@]([C@H](CC)C)([H])C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N)=O)CS)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CNC3=C2C=CC=C3)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C134H234N40O32S.C2HF3O2/c1-23-72(16)104(167-99(180)60-138)125(199)149-62-100(181)151-75(19)111(185)168-102(70(12)13)127(201)163-89(55-66(4)5)119(193)157-84(41-30-33-51-137)118(192)169-103(71(14)15)128(202)164-91(57-68(8)9)121(195)172-108(78(22)177)131(205)173-107(77(21)176)126(200)150-63-101(182)153-93(58-69(10)11)132(206)174-54-36-44-96(174)124(198)152-76(20)110(184)161-90(56-67(6)7)120(194)170-106(74(18)25-3)130(204)165-94(64-175)123(197)162-92(59-79-61-148-81-38-27-26-37-80(79)81)122(196)171-105(73(17)24-2)129(203)160-83(40-29-32-50-136)113(187)156-85(42-34-52-146-133(142)143)114(188)154-82(39-28-31-49-135)112(186)155-86(43-35-53-147-134(144)145)115(189)158-87(45-47-97(139)178)116(190)159-88(46-48-98(140)179)117(191)166-95(65-207)109(141)183;3-2(4,5)1(6)7/h26-27,37-38,61,66-78,82-96,102-108,148,175-177,207H,23-25,28-36,39-60,62-65,135-138H2,1-22H3,(H2,139,178)(H2,140,179)(H2,141,183)(H,149,199)(H,150,200)(H,151,181)(H,152,198)(H,153,182)(H,154,188)(H,155,186)(H,156,187)(H,157,193)(H,158,189)(H,159,190)(H,160,203)(H,161,184)(H,162,197)(H,163,201)(H,164,202)(H,165,204)(H,166,191)(H,167,180)(H,168,185)(H,169,192)(H,170,194)(H,171,196)(H,172,195)(H,173,205)(H4,142,143,146)(H4,144,145,147);(H,6,7)/t72-,73-,74-,75-,76-,77+,78+,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,102-,103-,104-,105-,106-,107-,108-;/m0./s1
InChi Key
DJXAVHHNEHIXKN-FXQKTPAXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-37504-1 |
|---|---|
| Supplier Part Number | 37504-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |