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Cayman 306-O12B
List Price
$405.00
Your Price
$405.00
Cayman 306-O12B - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-37549-25
MFG.PART:
37549-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
306-O12B is an ionizable cationic lipidoid.1 It has been used in the generation of lipid nanoparticles (LNPs). Intravenous administration of LNPs containing 306-O12B and encapsulating an mRNA reporter accumulate specifically in the mouse liver. LNPs containing 306-O12B and encapsulating mRNA encoding the Cas9 nuclease (mCas9) and single-guide RNA targeting Angptl3 (sgAngptl3), the gene encoding angiopoietin-related protein 3, have been used to induce CRISPR-mediated gene knockdown in mice resulting in a reduction of serum Angptl3 protein, LDL, and triglyceride levels.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
tetrakis(2-
CAS Number
2566523-06-4
Molecular Formula
C59H115N3O8S8
Formula Weight
1251.1
Purity
≥95%
Formulation(Request formulation change)
A solution in methyl acetate
Solubility(Learn about Variance in Solubility)
- Ethanol: 10 mg/mL
SMILES
O=C(OCCSSCCCCCCCC)CCN(CCCN(C)CCCN(CCC(OCCSSCCCCCCCC)=O)CCC(OCCSSCCCCCCCC)=O)CCC(OCCSSCCCCCCCC)=O
InChi Code
InChI=1S/C59H115N3O8S8/c1-6-10-14-18-22-26-48-71-75-52-44-67-56(63)32-40-61(41-33-57(64)68-45-53-76-72-49-27-23-19-15-11-7-2)38-30-36-60(5)37-31-39-62(42-34-58(65)69-46-54-77-73-50-28-24-20-16-12-8-3)43-35-59(66)70-47-55-78-74-51-29-25-21-17-13-9-4/h6-55H2,1-5H3
InChi Key
FTXIINBPTFOCHN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-37549-25 |
|---|---|
| Supplier Part Number | 37549-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 2566523-06-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |