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Cayman RN-1747
List Price
$85.00
Your Price
$85.00
Cayman RN-1747 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-37573-5
MFG.PART:
37573-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
RN-1747 is an agonist of transient receptor potential vanilloid 4 (TRPV4).1 It selectively induces calcium influx in HEK293 cells expressing human, rat, or mouse TRPV4 (EC50s = 0.77, 4.1, and 4 µM, respectively) over HEK293 cells expressing human TRPV1, TRPV3, or transient receptor potential melastatin 8 (TRPM8; EC50s = >100, >30, and >30 µM, respectively). RN-1747 (10 µM) induces inward current in Xenopus oocytes expressing human TRPV4. Topical, but not intravenous, administration of RN-1747 induces hypothermia in rats.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[(4-chloro-
CAS Number
1024448-59-6
Molecular Formula
C17H18ClN3O4S
Formula Weight
395.9
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: Soluble
- Methanol: Soluble
SMILES
ClC1=CC=C(S(=O)(N2CCN(CC2)CC3=CC=CC=C3)=O)C([N+]([O-])=O)=C1
InChi Code
InChI=1S/C17H18ClN3O4S/C18-15-6-7-17(16(12-15)21(22)23)26(24,25)20-10-8-19(9-11-20)13-14-4-2-1-3-5-14/h1-7,12H,8-11,13H2
InChi Key
ZNLVYSJQUMALEO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-37573-5 |
|---|---|
| Supplier Part Number | 37573-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1024448-59-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |