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Cayman 113-O12B
List Price $620.00 Your Price $620.00
Cayman 113-O12B - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-37671-25
MFG.PART: 37671-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
113-O12B is a disulfide bond-containing ionizable cationic lipidoid.1 It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. Subcutaneous administration of LNPs containing 113-O12B and encapsulating an mRNA reporter accumulate specifically in mouse lymph nodes. LNPs containing 113-O12B and encapsulating mRNA encoding ovalbumin reduce tumor growth and increase the number of tumoral CD8+ T cells, M1-like macrophages, and activated dendritic cells in an ovalbumin-expressing B16/F10 murine melanoma model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
tetrakis(2-
CAS Number
2803699-72-9
Molecular Formula
C57H111N3O8S8
Formula Weight
1223.0
Purity
≥98%
Formulation(Request formulation change)
A solution in methyl acetate
Solubility(Learn about Variance in Solubility)
- Ethanol: 10 mg/mL
SMILES
O=C(CCN(CCN(CCN(CCC(OCCSSCCCCCCCC)=O)CCC(OCCSSCCCCCCCC)=O)C)CCC(OCCSSCCCCCCCC)=O)OCCSSCCCCCCCC
InChi Code
InChI=1S/C57H111N3O8S8/c1-6-10-14-18-22-26-46-69-73-50-42-65-54(61)30-34-59(35-31-55(62)66-43-51-74-70-47-27-23-19-15-11-7-2)40-38-58(5)39-41-60(36-32-56(63)67-44-52-75-71-48-28-24-20-16-12-8-3)37-33-57(64)68-45-53-76-72-49-29-25-21-17-13-9-4/h6-53H2,1-5H3
InChi Key
YIMNDEVCHLNZOO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-37671-25 |
|---|---|
| Supplier Part Number | 37671-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 2803699-72-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |