We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman RS 25344 (hydrochloride)
List Price
$275.00
Your Price
$275.00
Cayman RS 25344 (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-37793-100
MFG.PART:
37793-100
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
RS 25344 is an inhibitor of phosphodiesterase 4 (PDE4; IC50 = 0.3 nM).1 It is selective for PDE4 over PDE1, -2, and -3 (IC50s = >100 µM for all). RS 25344 inhibits concanavalin A-induced IL-5 release and LPS-induced TNF-α release in isolated human peripheral blood mononuclear cells (PBMCs; EC50s = 0.3 and 5.4 nM, respectively).2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-(3-nitro phenyl)-3-(4- pyridinyl methyl)- pyrido[2,3-d] pyrimidine-2,4 (1H,3H)-dione
CAS Number
152815-28-6
Molecular Formula
C19H13N5O4 • HCl
Formula Weight
411.8
Purity
≥95%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 5 mg/mL
- DMSO: 15 mg/mL
SMILES
O=C1C2=CC=CN=C2N(C3=CC([N+]([O-])=O)=CC=C3)C(N1CC4=CC=NC=C4)=O.Cl
InChi Code
InChI=1S/C19H13N5O4.ClH/c25-18-16-5-2-8-21-17(16)23(14-3-1-4-15(11-14)24(27)28)19(26)22(18)12-13-6-9-20-10-7-13;/h1-11H,12H2;1H
InChi Key
ROSFKXDQMBPYQQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-37793-100 |
|---|---|
| Supplier Part Number | 37793-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 152815-28-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |