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Cayman C6 Nbd Ceramide (D18160); Purity- Greater Than Or Equal To
List Price
$686.00
Your Price
$686.00
Cayman C6 Nbd Ceramide (D18160); Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-62527-10
MFG.PART:
62527-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
CAY10747 is an inhibitor of the protein-protein interaction between heat shock protein 90 (Hsp90) and cell division cycle 37 (Cdc37) and a derivative of celastrol (Item No. ). It decreases protein levels of the Hsp90-Cdc37 complex and the Hsp90-Cdc37 clients phosphorylated Akt and Cdk4 in A549 cells when used at a concentration of 5 µM. CAY10747 inhibits proliferation of A549, MCF-7, HOS, and HepG2 cells (IC50s = 0.41, 0.64, 0.9, and 0.94 µM, respectively) and induces apoptosis in A549 cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(9β,13α,14β,
CAS Number
2413849-81-5
Molecular Formula
C42H48FNO6
Formula Weight
681.8
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 1 mg/ml
λmax
298, 422 nm
SMILES
O=C1C=C2C(C(C)=C1O)=CC=C3[C@]2(CC[C@]4([C@]5([H])C[C@@](CC[C@@]5(CC[C@]34C)C)(C(OCCCOC(/C=C(C#N)/C6=CC=C(F)C=C6)=O)=O)C)C)C
InChi Code
InChI=1S/C42H48FNO6/c1-26-30-12-13-33-40(4,31(30)23-32(45)36(26)47)17-19-42(6)34-24-39(3,15-14-38(34,2)16-18-41(33,42)5)37(48)50-21-7-20-49-35(46)22-28(25-44)27-8-10-29(43)11-9-27/h8-13,22-23,34,47H,7,14-21,24H2,1-6H3/b28-22+/t34-,38-,39-,40+,41-,42+/m1/s1
InChi Key
PNQKCDFOTMDGCU-PYZHFFOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-62527-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 62527-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 94885-02-6 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |