We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman BAY u9773
List Price $1,091.00 Your Price $1,091.00
Cayman BAY u9773 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-70770-500
MFG.PART: 70770-500
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
BAY u9773 is a cysteinyl leukotriene 1 (CysLT1) and CysLT2 receptor antagonist.1 It inhibits contractions induced by leukotriene D4 (LTD4; Item No. 20310) or LTC4 (Item No. 20210) in isolated guinea pig trachea, rat lung, ferret spleen, and sheep bronchus (PA2s = 6.8-7.4). BAY u9773 (0.1 mg/kg) suppresses airway hypersensitivity and bronchoalveolar lavage fluid (BALF) eosinophil infiltration in a guinea pig model of ovalbumin-induced asthma.2 It also increases the latency to generalized seizures and decreases the EEG amplitude in a mouse model of seizures induced by pentylenetetrazol (PTZ; Item No. 18682).3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4- [[(1R,2E,4E,6Z,9Z)- 1- [(1S)- 4- carboxy- 1- hydroxybutyl]- 2,4,6,9- pentadecatetraenyl]thio]- benzoic acid
CAS Number
154978-38-8
Molecular Formula
C27H36O5S
Formula Weight
472.6
Purity
≥95%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- DMF: 25 mg/mL
- DMSO: 25 mg/mL
- Ethanol: 25 mg/mL
- PBS (pH 7.2): .15 mg/mL
λmax
279 nm
SMILES
CCCCC/C=C\C\C=C/C=C\C=C/[C@@H](Sc1ccc(cc1)C(=O)O)C(O)CCCC(=O)O
InChi Code
InChI=1S/C27H36O5S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(28)15-14-17-26(29)30)33-23-20-18-22(19-21-23)27(31)32/h6-7,9-13,16,18-21,24-25,28H,2-5,8,14-15,17H2,1H3,(H,29,30)(H,31,32)/b7-6-,10-9-,12-11+,16-13+/t24-,25+/m0/s1
InChi Key
PKJINWOACFYDQN-RBVMPENBSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-70770-500 |
|---|---|
| Supplier Part Number | 70770-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -80 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 154978-38-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |

