We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Caymancehc; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
List Price
$95.00
Your Price
$95.00
Cayman -Cehc; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-89630-5
MFG.PART:
89630-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
MK-7655 is a β-lactamase inhibitor that inhibits hydrolysis of nitrocefin by KPC-2 β-lactamase from K. pneumoniae and AmpC β-lactamase from P. aeruginosa (IC50s = 210 and 465 nM, respectively). It restores imipenem-susceptibility in imipenem-resistant K. pneumoniae and P. aeruginosa when used at concentrations of 12.5 and 4.7 μM, respectively. MK-7655 also restores imipenem sensitivity to resistant clinical isolates of P. aeruginosa and K. pneumoniae (MIC50s = 0.25-2 and 8-16 μM in the presence and absence of MK-7655, respectively), but not A. baumannii. In vivo, MK-7655 (48.9 mg/kg per day) produces a bacteriostatic effect in mouse thigh models of K. pneumoniae and P. aeruginosa infection when administered with imipenem (Item No. ) and cilastatin (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
mono
CAS Number
1174018-99-5
Molecular Formula
C12H20N4O6S
Formula Weight
348.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 1 mg/ml
- DMSO: 10 mg/ml
- PBS (pH 7.2): 10 mg/ml
SMILES
O=C1N(OS(O)(=O)=O)[C@@H]2CC[C@@H](C(NC3CCNCC3)=O)[N@]1C2
InChi Code
InChI=1S/C12H20N4O6S/c17-11(14-8-3-5-13-6-4-8)10-2-1-9-7-15(10)12(18)16(9)22-23(19,20)21/h8-10,13H,1-7H2,(H,14,17)(H,19,20,21)/t9-,10+/m1/s1
InChi Key
SMOBCLHAZXOKDQ-ZJUUUORDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-89630-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 89630-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 178167-75-4 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |