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Cayman Trichostatin A; Purity- Greater Than Or Equal To 98%; Size
List Price
$88.00
Your Price
$88.00
Cayman Trichostatin A; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-89730-1
MFG.PART:
89730-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
PHPS1 is a cell-permeable, phosphotyrosine mimetic that inhibits the Src homology region 2 domain-containing phosphatase (SHP)-2 (IC50 = 2.1 µM; Ki = 0.73 µM). It is selective for SHP-2, inhibiting ECPTP, PTP1B, SHP-1, and mycobacterium MptpA at relatively higher concentrations (IC50s = 5.4, 19, 30, and 39 µM, respectively). PHPS1 has been shown to inhibit SHP-2-dependent cellular signaling and tumor cell colony formation.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4- [2- [1,5- dihydro- 3- (4- nitrophenyl)- 5- oxo- 1- phenyl- 4H- pyrazol- 4- ylidene]hydrazinyl]- benzenesulfonic acid
CAS Number
314291-83-3
Synonyms
- Phenylhydrazonopyrazolone sulfonate 1
- Protein Tyrosine Phosphatase Inhibitor V
- PTP Inhibitor V
Molecular Formula
C21H15N5O6S
Formula Weight
465.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- :
- DMF: 5 mg/mL
- DMSO: 5 mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
λmax
244, 299, 411 nm
SMILES
O=C1N(C2=CC=CC=C2)N=C(C3=CC=C([N+]([O-])=O)C=C3)/C1=N\NC4=CC=C(S(O)(=O)=O)C=C4
InChi Code
InChI=1S/C21H15N5O6S/c27-21-20(23-22-15-8-12-18(13-9-15)33(30,31)32)19(14-6-10-17(11-7-14)26(28)29)24-25(21)16-4-2-1-3-5-16/h1-13,22H,(H,30,31,32)/b23-20+
InChi Key
VIQSBJOMLQLAKC-BSYVCWPDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-89730-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 89730-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 58880-19-6 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |