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Cayman Trichostatin A; Purity- Greater Than Or Equal To 98%; Size
List Price
$441.00
Your Price
$441.00
Cayman Trichostatin A; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-89730-10
MFG.PART:
89730-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Trichostatin A is a potent, reversible inhibitor of class I, II, and IV histone deacetylases (HDACs). In human Jurkat T cells, trichostatin A arrests cell cycle progression in G1 and inhibits the activity of HDAC1 with an IC50 value of 70 nM.1 Trichostatin A selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7- [4- (dimethylamino)phenyl]- N- hydroxy- 4,6R- dimethyl- 7- oxo- 2E,4E- heptadienamide
CAS Number
58880-19-6
Synonyms
- TSA
Molecular Formula
C17H22N2O3
Formula Weight
302.4
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- 0.1 M HCl: 1.3 mg/ml
- DMF: 2 mg/ml
- DMSO: 2 mg/ml
λmax
265, 340 nm
SMILES
CN(C)C1=CC=C(C([C@H](C)/C=C(C)/C=C/C(N(O)[H])=O)=O)C=C1
InChi Code
InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
InChi Key
RTKIYFITIVXBLE-QEQCGCAPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-89730-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 89730-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 58880-19-6 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |