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Cayman Carnosol; Purity- Greater Than Or Equal To 96%; Size- 50 M
List Price
$1,528.00
Your Price
$1,528.00
Cayman Carnosol; Purity- Greater Than Or Equal To 96%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-89800-50
MFG.PART:
89800-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Carnosol is a phenol that has been found in rosemary (R. officinalis) and has diverse biological activities.1,2,3,4 It decreases nitric oxide (NO) production in mouse peritoneal exudate macrophages when used at concentrations ranging from 6 to 25 µM.1 Carnosol scavenges peroxyl and hydroxyl radicals and inhibits lipid peroxidation in cell-free assays.2 It inhibits 5-lipoxygenase (5-LO; IC50 = 0.1 µM for the recombinant human enzyme) and the synthesis of leukotrienes in human polymorphonuclear leukocytes (PMNs; IC50 = 7 µM).3 In vivo, carnosol (200 mg/kg) reduces mammary DNA adduct formation and tumorigenesis in a rat model of DMBA-induced mammary tumorigenesis.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,3,4,9,10,10aS- hexahydro- 5,6- dihydroxy- 1,1- dimethyl- 7- isopropyl- 2H- 9S,4aR- (epoxymethano)phenanthren- 12- one
CAS Number
5957-80-2
Synonyms
- NSC 39143
Molecular Formula
C20H26O4
Formula Weight
330.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: >35 mg/ml
- DMSO: >250 mg/ml
- Ethanol: >8 mg/ml
- Ethanol:PBS(pH 7.2)(1:1): 0.5 mg/ml
- PBS pH 7.2: <30 µg/ml
λmax
285 nm
SMILES
CC(C)c1cc2C3OC(=O)C4(CCCC(C)(C)C4C3)c2c(O)c1O
InChi Code
InChI=1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13?,14-,20?/m1/s1
InChi Key
XUSYGBPHQBWGAD-LQZXRHCMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 3 years
| SKU | CAYM-89800-50 |
|---|---|
| Featured | No |
| Supplier Part Number | 89800-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 5957-80-2 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |