We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Carbaprostacyclin Methyl Ester; Purity- Greater Than Or Eq
Product Description
Zileuton-d4 is intended for use as an internal standard for the quantification of zileuton (Item No. ) by GC- or LC-MS. Zileuton is a reversible 5-lipoxygenase (5-LO) inhibitor. It inhibits 5-LO activity in rat basophilic leukemia-1 (RBL-1) cell supernatant with an IC50 value of 0.5 µM. Zileuton inhibits leukotriene B4 (LTB4; Item No. ) production induced by the calcium ionophore A23187 (Item No. ) in purified human peripheral blood polymorphonuclear leukocytes (PMNLs; IC50 = 0.6 µM). Zileuton (10 mg/kg, p.o.) prevents antigen challenge-induced increases in specific lung resistance in a sheep model of asthma at 4 to 8 hours post-challenge following administration 2 hours pre-challenge. Formulations containing zileuton have been used in the prophylaxis and chronic treatment of asthma.
WARNING This product is not for human or veterinary use.
Technical Information
- DMSO: slightly soluble
- Methanol: very slightly soluble
Shipping & Storage Information
| SKU | CAYM-9000183-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 9000183-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 69552-55-2 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |