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Cayman Methylcarbamyl Paf C-8; Purity- Greater Than Or Equal To 9
List Price
$395.00
Your Price
$395.00
Cayman Methylcarbamyl Paf C-8; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-9000332-5
MFG.PART:
9000332-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
PF-04217903 is an inhibitor of c-Met (Ki = 4.8 nM). It is greater than 1,000-fold selective for c-Met over a panel of 150 kinases. PF-04217903 inhibits the proliferation of and induces apoptosis in GTL-16 gastric carcinoma cells (IC50s = 12 and 31 nM, respectively) as well as inhibits migration of NCI H441 lung cancer cells induced by hepatocyte growth factor (HGF; IC50 = 11 nM). It reduces tumor growth in a GTL-16 mouse xenograft model when administered at doses ranging from 1 to 30 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[1-(6-quinolinylmethyl)-
CAS Number
956905-27-4
Molecular Formula
C19H16N8O
Formula Weight
372.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 1 mg/ml
- DMSO: 2 mg/ml
- DMSO:PBS (pH 7.2)(1:8): 0.1 mg/ml
λmax
226, 315, 346 nm
SMILES
OCCN(N=C1)C=C1C2=CN=C3C(N(CC4=CC=C5C(C=CC=N5)=C4)N=N3)=N2
InChi Code
InChI=1S/C19H16N8O/c28-7-6-26-12-15(9-22-26)17-10-21-18-19(23-17)27(25-24-18)11-13-3-4-16-14(8-13)2-1-5-20-16/h1-5,8-10,12,28H,6-7,11H2
InChi Key
PDMUGYOXRHVNMO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-9000332-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 9000332-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |