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Cayman (S)-Acenocoumarol; Purity- Greater Than Or Equal To 98%; S
List Price
$601.00
Your Price
$601.00
Cayman (S)-Acenocoumarol; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-9000336-5
MFG.PART:
9000336-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
BMS-777607 is an inhibitor of the Met kinase family. It inhibits Ron, Met, Tyro-3, and AxI with IC50 values of 1.8, 3.9, 4.3, and 1.1 nM, respectively. At higher concentrations it is reported to inhibit Mer, FLT3, Aurora B, Lck, and VEGFR2 (IC50s = 14, 16, 78, 120, and 180 nM, respectively). In cancer cells, BMS-777607 induces polyploidy with multiple sets of chromosomes, as well as suppresses metastasis., In tumor xenograft models, BMS-777607 at 50 mg/kg/mouse inhibits the growth of tumor cells expressing Met/Ron.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[4-[(2-amino-3-chloro-
CAS Number
1025720-94-8
Synonyms
- BMS-817378
Molecular Formula
C25H19ClF2N4O4
Formula Weight
512.9
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/ml
- DMF:PBS (pH 7.2); (1:7): 0.1 mg/ml
- DMSO: 5 mg/ml
λmax
204, 289 nm
SMILES
NC1=C(Cl)C(OC2=CC=C(NC(C3=C(OCC)C=CN(C4=CC=C(F)C=C4)C3=O)=O)C=C2F)=CC=N1
InChi Code
InChI=1S/C25H19ClF2N4O4/c1-2-35-19-10-12-32(16-6-3-14(27)4-7-16)25(34)21(19)24(33)31-15-5-8-18(17(28)13-15)36-20-9-11-30-23(29)22(20)26/h3-13H,2H2,1H3,(H2,29,30)(H,31,33)
InChi Key
VNBRGSXVFBYQNN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-9000336-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 9000336-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 66556-78-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |