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Cayman PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)-d62 (sodium salt)
List Price
$194.00
Your Price
$194.00
Cayman PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)-d62 (sodium salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-9000414-50
MFG.PART:
9000414-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)-d62 (sodium salt) is intended for use as an internal standard for the quantification of PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) (Item No. 64920) by GC- or LC-MS.. The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (pH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins.3,4 Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see references 5 and 6.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-(1,2R-
Synonyms
- DPPI-3,4,5-P3-d62
- Phosphatidylinositol-3,4,5-trisphosphate C-16-d62
- PI(3,4,5)P3 (16:0/16:0)-d62
- PIP3[3,4,5](16:0/16:0)-d62
Molecular Formula
C41H16D62O22P4 • 4Na
Formula Weight
1201.3
Purity
≥99% deuterated forms (d1-
Formulation(Request formulation change)
A lyophilized powder
Solubility(Learn about Variance in Solubility)
- Water: 10 mg/mL
SMILES
O[C@@H]1[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@@H](O)[C@H]1OP([O-])(OCC(COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H
InChi Code
InChI=1S/C41H82O22P4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)57-31-33(59-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-58-67(55,56)63-38-36(44)39(60-64(46,47)48)41(62-66(52,53)54)40(37(38)45)61-65(49,50)51/h33,36-41,44-45H,3-32H2,1-2H3,(H,
InChi Key
ZSZXYWFCIKKZBT-ZJSKRBLYSA-J
Side Chain Carbon Sum
32:0
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 5 years
| SKU | CAYM-9000414-50 |
|---|---|
| Supplier Part Number | 9000414-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |