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Cayman SR 144528
List Price
$245.00
Your Price
$245.00
Cayman SR 144528 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-9000491-10
MFG.PART:
9000491-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
SR 144528 is a cannabinoid 2 (CB2) receptor antagonist (Ki = 0.6 nM). It is selective for CB2 over CB1 receptors in CHO Cells expressing the human receptors (Ki = 437 nM). SR 144528 reverses CP 55,940-induced inhibition of forskolin-induced adenylyl cyclase activity in CHO Cells expressing human CB2 receptors (EC50 = 10 nM). SR 144528 (0.01 mg/kg) reduces paw swelling in a mouse model of carrageenan-induced paw edema.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-
CAS Number
192703-06-3
Molecular Formula
C29H34ClN3O
Formula Weight
476.1
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL
SMILES
C[C@]1(C2)[C@H](NC(C3=NN(CC4=CC=C(C)C=C4)C(C5=CC(C)=C(Cl)C=C5)=C3)=O)C(C)(C)[C@@H]2CC1
InChi Code
InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1
InChi Key
SUGVYNSRNKFXQM-XRHWURSXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-9000491-10 |
|---|---|
| Supplier Part Number | 9000491-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 192703-06-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |