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Cayman Colchicine
List Price $37.00 Your Price $37.00
Cayman Colchicine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-9000760-250
MFG.PART: 9000760-250
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Colchicine is an inhibitor of microtubule polymerization (IC50 = 3.2 μM) that binds to tubulin, which disrupts spindle formation during mitosis.1 It inhibits growth of MCF-7 human breast carcinoma cells with an IC50 value of 13 nM.1 Colchicine has anti-inflammatory activity, inhibiting neutrophil motility and activity when used at a dose of 5 μmol/kg in a mouse model of gout and preventing the deposition of uric acid.2,3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-
CAS Number
64-86-8
Molecular Formula
C22H25NO6
Formula Weight
399.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: 25 mg/mL
- Ethanol: 25 mg/mL
λmax
202, 243, 352 nm
SMILES
COC1=C(OC)C=C2C(C(C([C@@H](NC(C)=O)CC2)=C3)=CC=C(OC)C3=O)=C1OC
InChi Code
InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
InChi Key
IAKHMKGGTNLKSZ-INIZCTEOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-9000760-250 |
|---|---|
| Supplier Part Number | 9000760-250 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 64-86-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |