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Cayman 3-Deaza-2-Deoxyadenosine; Purity- Greater Than Or Equal T
List Price
$210.00
Your Price
$210.00
Cayman 3-Deaza-2-Deoxyadenosine; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-9000786-5
MFG.PART:
9000786-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
R1487 is an inhibitor of p38α MAPK (IC50 = 10 nM). It is selective for p38α over p38β MAPK (Kds = 0.2 and 29 nM, respectively), as well as a panel of 306 additional kinases at 10 µM, but does inhibit 11 kinases by greater than 85% at 10 µM. R1487 inhibits LPS-induced IL-1β production in isolated human whole blood (IC50 = 170 nM). It also inhibits LPS-induced production of TNF-α and IL-6 in rats (ED50s = 0.8 and 0.4 mg/kg). R1487 reduces yeast-induced hyperalgesia in rats (ED50 = 5.5 mg/kg).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-(2,4-difluoro
CAS Number
449808-64-4
Molecular Formula
C19H18F2N4O3 • HCl
Formula Weight
424.8
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 1 mg/ml
- DMSO: 1 mg/ml
- DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
299, 349 nm
SMILES
O=C1C(OC2=CC=C(C=C2F)F)=CC3=C(N1C)N=C(NC4CCOCC4)N=C3.Cl
InChi Code
InChI=1S/C19H18F2N4O3.ClH/c1-25-17-11(10-22-19(24-17)23-13-4-6-27-7-5-13)8-16(18(25)26)28-15-3-2-12(20)9-14(15)21;/h2-3,8-10,13H,4-7H2,1H3,(H,22,23,24);1H
InChi Key
RQHSAIGGUWVOBG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-9000786-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 9000786-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 78582-17-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |