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Cayman Saquinavir (mesylate)
List Price
$329.00
Your Price
$329.00
Cayman Saquinavir (mesylate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-9001893-50
MFG.PART:
9001893-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Saquinavir is an HIV protease inhibitor (Kis = 0.12 and <0.1 nM for HIV-1 and HIV-2 protease, respectively).1 It is selective for HIV-1 and HIV-2 protease over human aspartic proteases, renin, pepsin, pepsinogen C, cathepsin D, and cathepsin E at 10 µM. Saquinavir inhibits replication of clinical isolates of HIV-1 in a variety of cell-based assays and has antiviral activity against HIV-1 in infected C8166 cells (IC50 = 2 nM).1,2 It also inhibits the activity of the severe acute respiratory coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro), with an IC50 value of 9.92 µM.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2S)-
CAS Number
149845-06-7
Synonyms
- Ro 31-
8959/003
Molecular Formula
C38H50N6O5 • CH3SO3H
Formula Weight
767.0
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: 1 mg/mL
- Methanol: 1 mg/mL
λmax
206, 239, 291 nm
SMILES
O=C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)[C@H](O)CN2[C@H](C(NC(C)(C)C)=O)C[C@@](CCCC3)([H])[C@@]3([H])C2)=O)CC(N)=O)C4=NC5=C(C=C4)C=CC=C5.CS(=O)(O)=O
InChi Code
InChI=1S/C38H50N6O5.CH4O3S/c1-38(2,3)43-37(49)32-20-26-14-7-8-15-27(26)22-44(32)23-33(45)30(19-24-11-5-4-6-12-24)41-36(48)31(21-34(39)46)42-35(47)29-18-17-25-13-9-10-16-28(25)40-29;1-5(2,3)4/h4-6,9-13,16-18,26-27,30-33,45H,7-8,14-15,19-23H2,1-3H3,(H2
InChi Key
IRHXGOXEBNJUSN-YOXDLBRISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-9001893-50 |
|---|---|
| Supplier Part Number | 9001893-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 149845-06-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |