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Cayman BODIPY-aminoacetaldehyde diethyl acetal
List Price $83.00 Your Price $83.00
Cayman BODIPY-aminoacetaldehyde diethyl acetal - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-9002056-50
MFG.PART: 9002056-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
BODIPY-aminoacetaldehyde diethyl acetal (BAAA-DA) is a stable precursor to BODIPY-aminoacetaldehyde, a cell-permeable fluorescent substrate for aldehyde dehydrogenase (ALDH).1,2 BODIPY-aminoacetaldehyde diethyl acetal is converted under acidic conditions to BODIPY-aminoacetaldehyde (BAAA).2 BAAA is cell-permeant and is converted intracellularly by ALDH to BODIPY aminoacetate (BAA), which is retained by cells and can be used to identify cells with high ALDH activity.1 BAA is a substrate for the efflux pump P-glycoprotein (P-gp) but co-application of BAAA with a P-gp inhibitor, such as verapamil (Item No. 14288), inhibits BAA efflux.2 BAAA-DA has been used to isolate human hematopoietic progenitor cells, which have high ALDH activity, and via flow cytometry to sort cancer stem cells that contain high levels of ALDH.1,3 BAA used in cells can be excited at 488 nm and displays an emission maximum of 512 nm.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(T-4)-[N-(2,2-diethoxyethyl)-5-[(3,5-dimethyl-2H-pyrrol-2-ylidene-kN)methyl]-1H-pyrrole-2-propanamidato-κN1]difluoro-boron
CAS Number
247069-93-8
Synonyms
- BAAA-DA
Molecular Formula
C20H28BF2N3O3
Formula Weight
407.3
Purity
≥95%
Emission
512 nm
Formulation(Request formulation change)
A solution in methyl acetate
SMILES
[F][B-]1([N]2C(C=C(C(C)=C3)[N+]1=C3C)=CC=C2CCC(NCC(OCC)OCC)=O)[F]
InChi Code
InChI=1S/C20H28BF2N3O3/c1-5-28-20(29-6-2)13-24-19(27)10-9-16-7-8-17-12-18-14(3)11-15(4)25(18)21(22,23)26(16)17/h7-8,11-12,20H,5-6,9-10,13H2,1-4H3,(H,24,27)
InChi Key
LHPURSCMUYRRRM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-9002056-50 |
|---|---|
| Supplier Part Number | 9002056-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 247069-93-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |