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Cayman WH-4-023
List Price $43.00 Your Price $43.00
Cayman WH-4-023 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-9002067-1
MFG.PART: 9002067-1
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
WH-4-023 is a selective inhibitor of the Src family of non-receptor tyrosine kinases (IC50s = 2 and 6 nM for Lck and Src, respectively)., It inhibits the related kinases p38α and KDR at >300-fold higher concentrations (IC50s = 1.3 and 0.65 µM, respectively). At 1 µM, it has been used in combination with PD 0325901 (Item No. ), CHIR99021 (Item No. ), and SB-590885 (Item No. ) to support self-renewal of naïve human embryonic stem cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(2,4-di methoxy phenyl)- N-[2-[[4- (4-methyl- 1-piperazinyl) phenyl]amino]- 4-pyrimidinyl]- carbamic acid, 2,6-dimethyl phenyl ester
CAS Number
837422-57-8
Molecular Formula
C32H36N6O4
Formula Weight
568.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 0.3 mg/mL
λmax
284 nm
SMILES
COC1=CC=C(N(C(OC2=C(C)C=CC=C2C)=O)C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=NC=C3)C(OC)=C1
InChi Code
InChI=1S/C32H36N6O4/c1-22-7-6-8-23(2)30(22)42-32(39)38(27-14-13-26(40-4)21-28(27)41-5)29-15-16-33-31(35-29)34-24-9-11-25(12-10-24)37-19-17-36(3)18-20-37/h6-16,21H,17-20H2,1-5H3,(H,33,34,35)
InChi Key
NBTNHSGBRGTFJS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-9002067-1 |
|---|---|
| Supplier Part Number | 9002067-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 837422-57-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |

