Cayman L-Canaline

L-Canaline is an aminooxy analog of ornithine that irreversibly inhibits aminotransferases (transaminases), including ornithine aminotransferase (K_i = 2 µM).^1,2,3 It forms oximes with α-keto acids and aldehydes, most notably with pyridoxal phosphate, an essential cofactor of aminotransferases.³ L-Canaline is naturally found in plants, including legumes, and is involved in the metabolism of L-canavanine, an aminooxy analog of arginine.⁴ It is cytotoxic to a range of organisms, including bacteria, insects, and parasites.^2,4,5

WARNING This product is not for human or veterinary use.