Cayman Prostaglandin D2 Dopamine

Prostaglandin D₂ (PGD₂; Item No. ), the major eicosanoid product of mast cells in the immune system, is also produced in the brain where it is involved in sleep regulatory mechanisms.^, Further pharmacological actions include inhibition of platelet aggregation, relaxation of vascular smooth muscle, and regulation of reproductive development. Dopamine-containing neurons in the brain are involved in reward-motivated behavior, motor control, and hormone release. Peripheral, paracrine actions of dopamine include the control of vasodilation, sodium excretion, insulin production, gastrointestinal motility, and the activity of lymphocytes.^, Catecholamines are known to stimulate prostanoid synthesis by acting as co-substrates. PGD₂ dopamine is a conjugate of the neurotransmitter dopmaine and PGD₂. It can be used to study the biological function of PGD₂ in the brain and periphery.

WARNING This product is not for human or veterinary use.