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Cayman Capsiate; Size- 50 Mg
Product Description
Capsiate is a non-pungent analog of capsaicin (Item Nos. 92350 | 10010743) that has been found in C. annuum and has diverse biological activities.1,2,3,4 It inhibits Src in, as well as VEGF-induced proliferation of and tube formation by, human umbilical vein endothelial cells (HUVECs) when used at concentrations ranging from 5 to 25 µM.1 Capsiate activates transient receptor potential vanilloid 1 (TRPV1) in HEK293 cells expressing the human channel (EC50 = 290 nM) and induces licking and biting behaviors, markers of nociception, in mice.2 Topical application of capsiate reduces antigen-induced increases in ear thickness in a mouse model of passive cutaneous anaphylaxis and decreases epidermal thickness and eosinophil and mast cell infiltration in a mouse model of atopic dermatitis.3 Capsiate (10 mg/kg) decreases body weight gain and perirenal fat weight, as well as increases oxygen consumption, fat oxidation, and carbohydrate oxidation, in a mouse model of ad libitum feeding-induced weight gain.4
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
Shipping & Storage Information
| SKU | CAYM-9002596-50 |
|---|---|
| Featured | No |
| Supplier Part Number | 9002596-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 205687-01-0 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |