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Cayman 5(Z),8(Z),11(Z)-Eicosatrienoic Acid; Purity- Greater Than
List Price
$317.00
Your Price
$317.00
Cayman 5(Z),8(Z),11(Z)-Eicosatrienoic Acid; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-90190-5
MFG.PART:
90190-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Chartreusin is an antibiotic originally isolated from S. chartreusis with diverse biological activities. It inhibits growth of S. aureus, B. subtilis, M. luteus, M. flavus, B. fragilis, C. difficile, C. perfringens, and P. acnes (MICs = 0.4-12.5 μg/ml). Chartreusin binds to DNA and induces electrophoretic shifts in both supercoiled and nicked plasmid DNA. It also inhibits strand-passing activity of topoisomerase II in a P4 unknotting assay. Chartreusin inhibits protein synthesis in chick embryo fibroblasts (CEFs) and mouse fibroblast 3T6 cells (IC50s = 7 and 70 μM, respectively). It is cytotoxic to human lung carcinoma A549 cells in vitro (IC50 = 95 nM) and increases median survival in P388 leukemia and B16 melanoma mouse tumor models when administered at a dose of 10 mg/kg per day.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
10-[[6-deoxy-
CAS Number
6377-18-0
Synonyms
- Antibiotic X 465A
- Lambdamycin
- NSC 5159
Molecular Formula
C32H32O14
Formula Weight
640.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- Acetone: soluble
- DMSO: 10 mg/ml
- Methanol: slightly soluble
λmax
236, 268, 331, 400, 423 nm
SMILES
OC1=C(C(OC2=C3C(C(O4)=O)=C(C)C=C2)=O)C3=C4C5=C1C=CC=C5O[C@@H]6O[C@H](C)[C@H](O)[C@H](O)[C@H]6O[C@]7([H])[C@H](O)[C@@H](OC)[C@@H](O)[C@@H](C)O7
InChi Code
InChI=1S/C32H32O14/c1-10-8-9-15-18-16(10)29(38)45-26-17-13(23(35)20(19(18)26)30(39)43-15)6-5-7-14(17)44-32-28(24(36)21(33)11(2)42-32)46-31-25(37)27(40-4)22(34)12(3)41-31/h5-9,11-12,21-22,24-25,27-28,31-37H,1-4H3/t11-,12-,21+,22+,24+,25-,27+,28-,31-,32+/m1/s1
InChi Key
PONPPNYZKHNPKZ-RYBWXQSLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-90190-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 90190-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 20590-32-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |