Sigma-Aldrich 4-Aminobenzoic Acid Reagen

4-Aminobenzoic acid (4-ABA) acts as an bacterial cofactor and participates in the synthesis of folic acid.[1] It is a versatile reagent for structure extension through linear hydrogen-bonding associations, involving both the carboxylic acid and amine functional groups.[1] Formation of 4-ABA monolayer film on glassy carbon electrode (GCE) by amino cation radical method has been described.[2] Molecular adducts of 4-ABA have been prepared and their characterization by infrared spectroscopy and X-ray diffration methods have been reported.[3]

4-Aminobenzoic acid may be used in the following studies:

• Covalent modification of glassy carbon electrode.[4]
• Synthesis of 1,4-(2-chlorobenzylidene)aminobenzoic acid (Schiff base).[5]
• Spectrophotometric determination of the trace amounts of dopamine, methyldopa and levodopa.[6]
• Synthesis of 1:1 proton-transfer compound with 5-sulfosalicylic acid.[1]

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